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Capsaicin from chili peppers and its analogues and their valued applications: An updated literature review

Na Wang, Xiang Zhou, Taihong Zhang, Wujun Jian, Zhaoju Sun, Pu‐Ying Qi, Yu‐Mei Feng, Hongwu Liu, Liwei Liu, Yang Song

2025Food Research International32 citationsDOIOpen Access PDF

Abstract

Chili peppers are widely sought after by consumers for not only their color, flavor, and nutritional properties but also their main component (capsaicin) various biological activities in diverse fields. Capsaicin (trans-8-methyl-N-vanillyl-6-nonenamide), the compound primarily responsible for the spicy flavor of peppers, remains a hot topic in the scientific community and shows the vast potential in various applications. Although many reviews focus comprehensively on capsaicin, most articles are limited to the medical field of capsaicin. This review provides an overview briefly of the capsaicin and its analogues in the fields of food, medicine and with a particular emphasis on their applications in agriculture and livestock farming. Overall, we aims is to expand the broad spectrum of applications for capsaicin and its analogues and explore their potential biological mechanisms. Finally, the challenges of capsaicin and future development prospects were discussed and proposed.

Topics & Concepts

CapsaicinChili pepperChemistryFood scienceInformation retrievalComputer scienceBiochemistryReceptorPepperIon Channels and ReceptorsPiperaceae Chemical and Biological StudiesBiochemical Analysis and Sensing Techniques
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