Supramolecular gel formation regulated by water content in organic solvents: self-assembly mechanism and biomedical applications
Lieqiang Liao, Xinjian Jia, Haoxiang Lou, Jinlian Zhong, Huijin Liu, Shunming Ding, Chao Chen, Sanguo Hong, Xuzhong Luo
Abstract
O/DMSO, v/v = 90/10) was evaluated, and the drug controlled release process was consistent with a first-order release mechanism. The human umbilical venous endothelial cell culture results showed that the PDA-N4 xerogel has good cytocompatibility, which implied that the gels have potential biological application in tissue engineering and controlled drug release.
Topics & Concepts
Supramolecular chemistryStackingHydrogen bondChemistrySelf-assemblySolventIntermolecular forceAmidePyridinePolymer chemistryChemical engineeringCrystal structureCrystallographyOrganic chemistryMoleculeEngineeringSupramolecular Self-Assembly in MaterialsSupramolecular Chemistry and ComplexesNanoplatforms for cancer theranostics