A/(H1N1) pdm09 NS1 promotes viral replication by enhancing autophagy through hijacking the IAV negative regulatory factor LRPPRC
Xing Guo, Zhenyu Zhang, Chaohui Lin, Huiling Ren, Yijing Li, Yuan Zhang, Yuxing Qu, Hongxin Li, Saiwen Ma, Huijuan Xia, Rongkuan Sun, Haoyu Zu, Yuezhi Lin, Xiaojun Wang
Abstract
: WSN recombinant strain in which NS1 was replaced with that of SC09.
Topics & Concepts
BiologyBECN1AutophagyHEK 293 cellsViral replicationCell biologyVirusVirologyCell cultureGeneticsApoptosisAutophagy in Disease and TherapyInfluenza Virus Research StudiesMosquito-borne diseases and control