Marburg Multiple Sclerosis Variant: Complete Remission with Very Early Administration of Mitoxantrone—A Case Report
Nicolas Capet, Michaël Levraut, Adrien Delourme, Oceane Thomel-Rocchi, Veronique Bourg, Philippe Cabre, Fanny Burel‐Vandenbos, Lydiane Mondot, Christine Lebrun‐Frénay
Abstract
Marburg variant is a severe and fulminant pseudotumor form of multiple sclerosis (MS) with high morbidity and mortality rates. Because of its scarcity, it remains incompletely characterized and physicians' experiences will influence the treatment. We report the inflammatory explosive case of a 31-year-old woman presenting with rapid neurological degradation of histology proven Marburg's disease, successfully treated with early administration of Mitoxantrone (MITX). To our knowledge, it is the first case describing complete remission after MITX in a biopsy-proven condition.
Topics & Concepts
MitoxantroneMedicineMultiple sclerosisNeurologyComplete remissionInternal medicineAdministration (probate law)OncologyImmunologyPsychiatryChemotherapyLawPolitical scienceMultiple Sclerosis Research StudiesHerpesvirus Infections and TreatmentsBartonella species infections research