Antibacterial electrospun nanomat from nigella/PVA system embedded with silver
Ayub Ali, Syed Maminul Islam, Md. Mohebbullah, Md Nur Uddin, Md. Tofazzal Hossain, Sonjit Kumar Saha, Mohammad Salman Ibna Jamal
Abstract
The present study involves the preparation and characterization of antibacterial nanofibers made from nigella/PVA mixer along with silver nanoparticles. Silver nanoparticles were efficiently synthesized by reduction of AgNO3 while alcoholic extraction process was used to extract the medicinal constituents form nigella. Then the resulting solution was electrospun into nanofibers by electrospinning technique under optimum processing conditions. The developed nanofibrous mat was characterized by bacterial assay, moisture management tester (MMT), thermal analyzer, scanning electron microscope (SEM), and FTIR to evaluate its antibacterial, moisture, thermal, morphological, and bonding behavior. The agar diffusion method had been used to evaluate the antibacterial activity against Staphylococcus aureus (S. aureus) bacteria revealing the formation of inhibition zone with a value around 18.66 ± 2 mm. Besides, the developed nanomat showed enhanced moisture and thermal properties having average diameter of 223 ± 20.5 nm. In addition, the presence of characteristic peaks in FTIR spectra revealed all the desired components are present in the developed nanofibrous mat.