Identification of a novel leptin receptor (LEPR) variant and proof of functional relevance directing treatment decisions in patients with morbid obesity
Franziska Voigtmann, Philipp Wolf, Kathrin Landgraf, Robert Stein, Jürgen Kratzsch, Samuel Schmitz, Rami Abou Jamra, Matthias Blüher, Jens Meiler, Annette G. Beck‐Sickinger, Wieland Kieß, Antje Körner
Topics & Concepts
Leptin receptorLeptinCompound heterozygosityLoss of heterozygosityEndocrinologyInternal medicineMutationMutantReceptorBiologyPhosphorylationObesityGeneAlleleGeneticsMedicineRegulation of Appetite and ObesityAdipokines, Inflammation, and Metabolic DiseasesBiochemical Analysis and Sensing Techniques