Assessment of the structure-activity relationship and antileukemic activity of diacylpyramide compounds as human ClpP agonists
Ranran Zhang, Pengyu Wang, Bingyan Wei, Liang Chen, Xiaomin Song, Yihui Pan, Jiahui Li, Jianhua Gan, Tao Zhang, Cai‐Guang Yang, Cai‐Guang Yang
Topics & Concepts
ChemistryIn vitroIn vivoCell cultureMyeloid leukemiaApoptosisCell growthAllosteric regulationCell biologyMitochondrial respiratory chainProgrammed cell deathMechanism of actionBiochemistryReceptorMitochondrionCancer researchBiologyBiotechnologyGeneticsRetinoids in leukemia and cellular processesUbiquitin and proteasome pathwaysDrug Transport and Resistance Mechanisms