Design and synthesis of new disubstituted benzoxazolone derivatives that act as iNOS inhibitors with potent anti-inflammatory activity against LPS-induced acute lung injury (ALI)
Li Tang, Xiaohui Gao, Bei Zhao, Jie‐ran Luo, Xin-yang Shi, Rui Ge, Shurong Ban, Qingshan Li
Topics & Concepts
ChemistryIn vivoPharmacologyIC50In vitroAnti-inflammatoryNitric oxideInflammationBiochemistryImmunologyMedicineBiologyBiotechnologyOrganic chemistrySynthesis of heterocyclic compoundsEicosanoids and Hypertension PharmacologySynthesis and Catalytic Reactions