Litcius/Paper detail

Rh(<scp>iii</scp>)-Catalyzed C(sp<sup>2</sup>)–H functionalization/cyclization cascade of <i>N</i>-carboxamide indole and iodonium reagents for access to indoloquinazolinone derivatives

Zhipeng Han, Mengmeng Xu, Ruiying Zhang, Xiaoping Xu, Shun‐Jun Ji

2021Green Chemistry50 citationsDOI

Abstract

The sustainable synthesis of indoloquinazolinone derivatives from N -methoxycarbamoyl indoles and iodonium ylide reagents in methanol is described.

Topics & Concepts

ChemistryIndole testReagentCatalysisSurface modificationMethanolCascadeMedicinal chemistryYlideCombinatorial chemistryOrganic chemistryChromatographyPhysical chemistryCatalytic C–H Functionalization MethodsQuinazolinone synthesis and applicationsOxidative Organic Chemistry Reactions