A rapid LC-MS/MS method for the simultaneous quantification of ivacaftor, lumacaftor, elexacaftor, tezacaftor, hexyl-methyl ivacaftor and ivacaftor carboxylate in human plasma
Yi Zheng, Steeve Rouillon, Mohamed Khemakhem, David Balakirouchenane, Gabrielle Lui, Seef Abdalla, Mohammed Rohi Sanoufi, Lucie Sauvaitre, Laure Thebault, Déborah Hirt, Jean‐Marc Tréluyer, Inès Gana, Sihem Benaboud, Léo Froelicher Bournaud
Topics & Concepts
IvacaftorChemistryHuman plasmaChromatographyBiochemistryGeneCystic fibrosis transmembrane conductance regulatorCystic Fibrosis Research AdvancesAsthma and respiratory diseasesInhalation and Respiratory Drug Delivery