The human mitochondrial 12S rRNA m4C methyltransferase METTL15 is required for mitochondrial function
Hao Chen, Zhennan Shi, Jiaojiao Guo, Kao-Jung Chang, Qianqian Chen, Cong-Hui Yao, Marcia C. Haigis, Yang Shi
Abstract
C methylation on prokaryotic ribosomes and eukaryotic mitochondrial ribosomes.
Topics & Concepts
BiologyMitochondrial ribosomeMitochondrial DNARibosomal RNAMT-RNR1MethylationRibosomeRNAMolecular biologyGeneticsGeneCell biologyRNA modifications and cancerRNA and protein synthesis mechanismsEpigenetics and DNA Methylation