Food and Nutrition in the Pathogenesis of Liver Damage
Andrea Mega, Luca Marzi, Michael Kob, Andrea Piccin, Annarosa Floreani
Abstract
The liver is an important organ and plays a key role in the regulation of metabolism and in the secretion, storage, and detoxification of endogenous and exogenous substances. The impact of food and nutrition on the pathophysiological mechanisms of liver injury represents a great controversy. Several environmental factors including food and micronutrients are involved in the pathogenesis of liver damage. Conversely, some xenobiotics and micronutrients have been recognized to have a protective effect in several liver diseases. This paper offers an overview of the current knowledge on the role of xenobiotics and micronutrients in liver damage.
Topics & Concepts
XenobioticDetoxification (alternative medicine)MicronutrientPathogenesisLiver injuryBiologyEndogenyLiver damagePhysiologyMedicineImmunologyPharmacologyEndocrinologyPathologyBiochemistryEnzymeAlternative medicineLiver Disease Diagnosis and TreatmentDrug-Induced Hepatotoxicity and ProtectionDiet, Metabolism, and Disease