Melatonin protects against defects induced by Enniatin B1 during porcine early embryo development
Xiangyu Wang, Mingju Sun, Jingyu Li, Xuexiong Song, Hongbin He, Yanjun Huan
Abstract
remarkably decreased. Whereas EB1-exposed embryos were treated with melatonin, these disorders were obviously ameliorated, and the development ability of embryos was also rescued. In conclusion, EB1 exerted detrimental effects on porcine early embryos, while melatonin effectively rescued EB1-mediated defects in embryos. This work provides a novel insight into the improvement of embryo quality and the promotion of human and animal reproduction.
Topics & Concepts
MelatoninEmbryoEmbryogenesisCell biologyEndocrinologyAndrologyInternal medicineBiologyChemistryMedicineDiet, Metabolism, and DiseaseBirth, Development, and HealthReproductive Biology and Fertility