Co-assembled and self-delivered epitope/CpG nanocomplex vaccine augments peptide immunogenicity for cancer immunotherapy
Xiaoguang Shi, Huijuan Song, Changrong Wang, Chuangnian Zhang, Pingsheng Huang, Deling Kong, Jianhua Zhang, Weiwei Wang
Topics & Concepts
ImmunogenicityEpitopePeptideCytotoxic T cellPeptide vaccineAdjuvantCross-presentationCancer immunotherapyCTL*VaccinationCancer vaccineImmunotherapyImmunizationCpG siteCancer researchCD8AntigenImmune systemChemistryMHC class IImmunologyMedicineBiochemistryIn vitroGene expressionGeneDNA methylationImmunotherapy and Immune Responsesvaccines and immunoinformatics approachesRNA Interference and Gene Delivery