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Gold-Conjugated Curcumin as a Novel Therapeutic Agent against Brain-Eating Amoebae

Mohammad Ridwane Mungroo, Ayaz Anwar, Naveed Ahmed Khan, Ruqaiyyah Siddiqui

2020ACS Omega38 citationsDOIOpen Access PDF

Abstract

, respectively. These findings are remarkable and suggest that clinically available curcumin and our gold-conjugated curcumin nanoparticles hold promise in the improved treatment of fatal infections caused by brain-eating amoebae and should serve as a model in the rationale development of therapeutic interventions against other infections.

Topics & Concepts

Naegleria fowleriCurcuminAcanthamoebaMicrobiologyMeningoencephalitisProtozoaColloidal goldChemistryVirologyBiologyMedicinePharmacologyNanotechnologyNanoparticleMaterials scienceHeme Oxygenase-1 and Carbon MonoxideLegionella and Acanthamoeba researchCurcumin's Biomedical Applications
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