Microglial NLRP3 inflammasome activation mediates diabetes-induced depression-like behavior via triggering neuroinflammation
Wenjun Su, Jiamei Li, Ting Zhang, Zhiyong Cao, Ting Hu, Shi-Yang Zhong, Zhang-Yang Xu, Hong Gong, Chunlei Jiang
Topics & Concepts
InflammasomeNeuroinflammationTXNIPDiabetes mellitusMicrogliaTLR4EndocrinologyInternal medicineMedicineHippocampal formationHippocampusInflammationOxidative stressThioredoxinTryptophan and brain disordersInflammasome and immune disordersNeuroinflammation and Neurodegeneration Mechanisms