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Effect of graphene oxide and gold nanoparticles on kidney parameters of male mice

Esraa H. Karsh, Rua J. Kadhim, Majid S. Jabir

2020AIP conference proceedings11 citationsDOI

Abstract

In this study we investigated the toxicity of Graphene oxide and Gold nanoparticles on kidney function parameters using Animals model. The nanoparticles were confirmed using different parameters like UV visible spectroscopy. The morphology was characterized by SEM. Moreover, their effectiveness in kidney parameters had been studied. These parameters included measurement of urea, and creatinine levels and histopathology sections for kidney after injection of nanoparticles intraperitoneal in male albino mice. The results of biochemical tests are showed no significant changes in urea, creatinine concentration compared with control group. Then we confirmed our results using histology sections of kidney. In conclusion there are no significant differences in levels of urea, creatinine between when compared with control group. So the results indicate that Graphene and Gold nanoparticles have no toxic effect on kidney of male mice.

Topics & Concepts

CreatinineGrapheneUreaKidneyMaterials scienceColloidal goldRenal functionNanoparticleHistopathologyInternal medicineChemistryNanotechnologyMedicinePathologyBiochemistryGraphene and Nanomaterials ApplicationsNanoparticles: synthesis and applications
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