Structural insights into cytokine cleavage by inflammatory caspase-4
Pascal Devant, Ying Dong, Julian Mintseris, Weiyi Ma, Steven P. Gygi, Hao Wu, Jonathan C. Kagan
Topics & Concepts
CaspaseCaspase 1Cell biologyCleaveInnate immune systemCleavage (geology)BiologyInflammasomeChemistryBiochemistryEnzymeApoptosisReceptorProgrammed cell deathPaleontologyFracture (geology)Inflammasome and immune disordersPhagocytosis and Immune RegulationCell death mechanisms and regulation