Gout and pseudo-gout-related crystals promote GLUT1-mediated glycolysis that governs NLRP3 and interleukin-1β activation on macrophages
Félix Renaudin, Lucie Orliaguet, Florence Castelli, François Fenaille, Aurélie Prignon, Fawaz Alzaïd, Christèle Combes, Aurélie Delvaux, Yasmina Adimy, Martine Cohen‐Solal, Pascal Richette, Thomas Bardin, Jean‐Pierre Riveline, Nicolas Venteclef, Frédéric Lioté, L. Campillo-Gimenez, Hang‐Korng Ea
Topics & Concepts
GLUT1GoutGlucose uptakeInflammationGlycolysisGlucose transporterAnaerobic glycolysisGlucose Transporter Type 1MedicineIn vivoInternal medicineEndocrinologyBiochemistryChemistryBiologyInsulinMetabolismBiotechnologyGout, Hyperuricemia, Uric AcidInflammasome and immune disordersMagnesium in Health and Disease