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Targeting the chromatin binding of exportin-1 disrupts NFAT and T cell activation

Yifan Chen, Maryam Ghazala, Ryan M. Friedrich, Brittany Cordova, Frederick N. Petroze, Ramya Srinivasan, Kevin Allan, David Yan, Joel L. Sax, Kelley Carr, Suzanne L. Tomchuck, Yuriy Fedorov, Alex Y. Huang, Amar Desai, Drew Adams

2024Nature Chemical Biology20 citationsDOI

Topics & Concepts

ChromatinNFATBiologyTranscription factorCell biologyCancer researchGeneticsDNAGeneNuclear Structure and FunctionGenomics and Chromatin DynamicsProtein Degradation and Inhibitors
Targeting the chromatin binding of exportin-1 disrupts NFAT and T cell activation | Litcius