The transcription factor Sp1 modulates RNA polymerase III gene transcription by controlling BRF1 and GTF3C2 expression in human cells
Feixia Peng, Ying Zhou, Juan Wang, Baoqiang Guo, Yun Wei, Huan Deng, Zihui Wu, Cheng Zhang, Kaituo Shi, Yuan Li, Xin Wang, Paul Shore, Shasha Zhao, Wensheng Deng
Abstract
P2. These findings indicate that Sp1 controls Pol III-directed transcription and shed light on how Sp1 regulates cancer cell proliferation.
Topics & Concepts
Transcription factorTranscription (linguistics)RNA polymerase IIRNA polymeraseGene expressionSigma factorGeneGeneral transcription factorPolymeraseTranscription factor II DCell biologyMolecular biologyBiologyRNAPromoterGeneticsPhilosophyLinguisticsGenomics and Chromatin DynamicsRNA modifications and cancerRNA Research and Splicing