CONN functional connectivity toolbox: RRID SCR_009550, release 21
Alfonso Nieto-Castañón, Susan Whitfield‐Gabrieli
Abstract
CONN 21 is a Matlab-based cross-platform software for the computation, display, and analysis of functional connectivity in fMRI (fcMRI). Connectivity measures include seed-to-voxel connectivity maps, ROI-to-ROI connectivity matrices, graph properties of connectivity networks, generalized psychophysiological interaction models (gPPI), intrinsic connectivity, local correlation, global correlation, inter-hemispheric correlation, independent component analyses (ICA), functional connectivity multivariate pattern analyses (fc-MVPA), and dynamic component analyses (dyn-ICA). CONN is available for resting state data (rsfMRI) as well as task-related designs. It covers the entire pipeline from raw fMRI data to hypothesis testing, including spatial coregistration, ART-based scrubbing, aCompCor strategy for control of physiological and movement confounds, first-level connectivity estimation, and second-level random-effect analyses and hypothesis testing.