A peptide-functionalised dendronised polymer for selective transfection in human liver cancer cells
Meenu Chopra, Agustin Sgro, Marck Nörret, Pilar Blancafort, K. Swaminathan Iyer, Cameron W. Evans
Abstract
A dendronised polymer functionalised with SP94 targeting peptide achieves highly selective transient transfection of liver cancer cells over normal non-transformed hepatocytes.
Topics & Concepts
ChemistryTransfectionPeptideLiver cancerCancer cellCancerCancer researchBiophysicsBiochemistryMolecular biologyGeneInternal medicineMedicineBiologyRNA Interference and Gene DeliveryImmunotherapy and Immune ResponsesAdvanced biosensing and bioanalysis techniques