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Single-cell mutation analysis of clonal evolution in myeloid malignancies

Linde A. Miles, Robert L. Bowman, Tiffany R. Merlinsky, Isabelle Csete, Aik T. Ooi, Robert Durruthy-Durruthy, Michael Bowman, Christopher Famulare, Minal Patel, Pedro Méndez, Chrysanthi Ainali, Benjamin Demaree, Cyrille L. Delley, Adam R. Abate, Manimozhi Manivannan, Sombeet Sahu, Aaron D. Goldberg, Kelly L. Bolton, Ahmet Zehir, Raajit K. Rampal, Martin Carroll, Sara E. Meyer, Aaron D. Viny, Ross L. Levine

2020Nature530 citationsDOIOpen Access PDF

Topics & Concepts

BiologySomatic evolution in cancerMyeloidGeneticsEpigeneticsSomatic cellClonal selectionMyeloid leukemiaGermline mutationAlleleImmunophenotypingMutationGeneCancer researchImmunologyFlow cytometryAcute Myeloid Leukemia ResearchMyeloproliferative Neoplasms: Diagnosis and TreatmentCancer Genomics and Diagnostics
Single-cell mutation analysis of clonal evolution in myeloid malignancies | Litcius