Development of potent and selective degraders of PI5P4Kγ
Wenzhi Ji, Eric S. Wang, Theresa Manz, Jie Jiang, Katherine A. Donovan, Xianmixinuer Abulaiti, Eric S. Fischer, Lewis C. Cantley, Tinghu Zhang, Nathanael S. Gray
Topics & Concepts
KinaseChemistryProteasomeContext (archaeology)ProteomeFunction (biology)UbiquitinCell biologyPhosphatidylinositolSignal transductionComputational biologyBiochemistryBiologyGenePaleontologyUbiquitin and proteasome pathwaysProtein Degradation and InhibitorsCellular transport and secretion