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Feasibility of gastric endoscopic submucosal dissection in elderly patients aged ≥ 80 years

Yasuhiro Inokuchi, Ayaka Ishida, Kei Hayashi, Yoshihiro Kaneta, Hayato Watanabe, Kazuki Kano, Mitsuhiro Furuta, Kosuke Takahashi, Hirohito Fujikawa, Takanobu Yamada, Kouji Yamamoto, Nozomu Machida, Takashi Ogata, Takashi Oshima, Shin Maeda

2022World Journal of Gastrointestinal Endoscopy14 citationsDOIOpen Access PDF

Abstract

BACKGROUND: Endoscopic resection, especially endoscopic submucosal dissection (ESD), is increasingly performed in elderly patients with early gastric cancer, and lesions beyond the expanded indications are also resected endoscopically in some patients. It is essential to assess whether gastric ESD is safe and suitable for elderly patients and investigate what type of lesions carry an increased risk of ESD-related complications. AIM: To assess the efficacy and feasibility of gastric ESD for elderly patients, and define high-risk lesions and prognostic indicators. METHODS: < 0.05 was considered statistically significant. RESULTS: < 0.001). CONCLUSION: Gastric ESD is feasible even in patients aged ≥ 80 years. Observation without additional surgery after noncurative ESD is reasonable, especially in elderly patients with CCI ≥ 2.

Topics & Concepts

MedicineEndoscopic submucosal dissectionCancerExact testProportional hazards modelSurgeryMann–Whitney U testHazard ratioSurvival analysisInternal medicineLog-rank testGastroenterologyConfidence intervalGastric Cancer Management and OutcomesEsophageal Cancer Research and TreatmentGastrointestinal Tumor Research and Treatment
Feasibility of gastric endoscopic submucosal dissection in elderly patients aged ≥ 80 years | Litcius