Neutrophil recruitment and leukocyte response following focused ultrasound and microbubble mediated blood-brain barrier treatments
Charissa Poon, Carly Pellow, Kullervo Hynynen
Abstract
This study provides evidence that the cellular aspect of the peripheral immune response triggered by FUS+MB BBB treatments begins immediately after sonication, and emphasizes the importance for further investigations to be conducted to understand leukocyte dynamics and cerebral blood flow responses to FUS+MB BBB treatments.
Topics & Concepts
Blood–brain barrierMicrobubblesInflammationImmune systemMicrogliaPathologyMedicineImmunologyBiologyNeuroscienceCentral nervous systemUltrasoundRadiologyUltrasound and Hyperthermia ApplicationsBarrier Structure and Function StudiesPhotoacoustic and Ultrasonic Imaging