A Re-emergence of Subacute Sclerosing Panencephalitis in the United Kingdom
Helen Campbell, Jamie Lopez Bernal, Antoaneta Bukasa, Nick Andrews, Elaine Baker, Polly Maunder, Anne Marie Winstone, Mary Ramsay, Christopher Verity, Kevin Brown
Abstract
New pediatric and adult subacute sclerosing panencephalitis cases between 1996 and 2020 were reported based on an established UK registry with no evidence of under-ascertainment using a separate pediatric surveillance system. After 15 years with no pediatric UK-acquired cases, 3 cases arose from 2017 after increased measles. Modeling suggested this was in line with measles notifications, underreporting of laboratory-confirmed measles or increased subacute sclerosing panencephalitis risk.
Topics & Concepts
Subacute sclerosing panencephalitisMeaslesMedicinePediatricsMeasles virusPathologyVaccinationVirology and Viral DiseasesSyphilis Diagnosis and TreatmentVaccine Coverage and Hesitancy