PPARγ-mediated microglial activation phenotype is involved in depressive-like behaviors and neuroinflammation in stressed C57BL/6J and ob/ob mice
Xiaqing Qin, Wei Wang, Huiran Wu, Dexiang Liu, Rui Wang, Jingjing Xu, Hong Jiang, Fang Pan
Topics & Concepts
NeuroinflammationEndocrinologyInternal medicinePeroxisome proliferator-activated receptorBehavioural despair testAgonistTail suspension testProinflammatory cytokineMicrogliaPioglitazoneHippocampusInflammationOpen fieldReceptorTumor necrosis factor alphaChemistryMedicineAntidepressantDiabetes mellitusType 2 diabetesTryptophan and brain disordersNeuroinflammation and Neurodegeneration MechanismsGut microbiota and health