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The development and validation of a novel LC-MS/MS method for the simultaneous quantification of Molnupiravir and its metabolite ß-d-N4-hydroxycytidine in human plasma and saliva

Alieu Amara, Sujan Dilly Penchala, Laura Else, Colin Hale, Richard J. Fitzgerald, Lauren Walker, Rebecca Lyons, Tom Fletcher, Saye Khoo

2021Journal of Pharmaceutical and Biomedical Analysis82 citationsDOIOpen Access PDF

Topics & Concepts

ChemistryChromatographyMetaboliteProtein precipitationAnalyteHuman plasmaAcetonitrileSalivaBiochemistrySARS-CoV-2 detection and testingRespiratory viral infections researchBiosensors and Analytical Detection
The development and validation of a novel LC-MS/MS method for the simultaneous quantification of Molnupiravir and its metabolite ß-d-N4-hydroxycytidine in human plasma and saliva | Litcius