Litcius/Paper detail

Discovery of novel benzofuran-based derivatives as acetylcholinesterase inhibitors for the treatment of Alzheimer's disease: Design, synthesis, biological evaluation, molecular docking and 3D-QSAR investigation

Somaia S. Abd El‐Karim, Manal M. Anwar, Nesreen S. Ahmed, Yasmin M. Syam, Samia A. Elseginy, Hanan F. Aly, Eman A. Younis, Wagdy K. B. Khalil, Kawkab A. Ahmed, Faten F. Mohammed, Maha Z. Rizk

2023European Journal of Medicinal Chemistry30 citationsDOIOpen Access PDF

Topics & Concepts

ChemistryAcetylcholinesteraseDocking (animal)DPPHGlutathionePharmacologyBenzofuranStereochemistryQuantitative structure–activity relationshipAntioxidantAcute toxicityDonepezilBiochemistryEnzymeToxicityOrganic chemistryInternal medicineMedicineDementiaDiseaseNursingCholinesterase and Neurodegenerative DiseasesComputational Drug Discovery MethodsSynthesis and biological activity