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Design and synthesis of triazole-functionalized isatin hybrids with potent anti-proliferative action against triple-negative breast cancer MDA-MB-231 cell line: a hybrid pharmacophore approach

Jyoti Rasgania, Renu Gavadia, Surendra Nimesh, Lacy Loveleen, Komal Jakhar

2023Journal of the Iranian Chemical Society10 citationsDOI

Topics & Concepts

IsatinPharmacophoreChemistryMoietyTriple-negative breast cancerDocking (animal)StereochemistryCombinatorial chemistrySubstituentIC50In vitroBiochemistryBreast cancerCancerBiologyOrganic chemistryMedicineGeneticsNursingSynthesis and biological activityClick Chemistry and ApplicationsSynthesis and Biological Evaluation
Design and synthesis of triazole-functionalized isatin hybrids with potent anti-proliferative action against triple-negative breast cancer MDA-MB-231 cell line: a hybrid pharmacophore approach | Litcius