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Endothelial Dysfunction: From a Pathophysiological Mechanism to a Potential Therapeutic Target

Pasquale Ambrosino, Guıdo Grassı, Mauro Maniscalco

2021Biomedicines19 citationsDOIOpen Access PDF

Abstract

The endothelium is considered the largest organ of the body, composed of a monolayer of endothelial cells (ECs) lining the interior surface of blood and lymphatic vessels [...].

Topics & Concepts

EndotheliumLymphatic systemLymphatic EndotheliumPathophysiologyEndothelial dysfunctionMechanism (biology)Cell biologyMedicineCancer researchImmunologyPathologyBiologyInternal medicinePhilosophyEpistemologyApelin-related biomedical researchNitric Oxide and Endothelin EffectsAngiogenesis and VEGF in Cancer