Nitisinone attenuates cartilage degeneration and subchondral osteoclastogenesis in osteoarthritis and concomitantly inhibits the cGAS/STING/NF-κB pathway
T. Yang, Haiwei Ma, Hehuan Lai, Yahong Lu, Kainan Ni, Xingyu Hu, Yang Zhou, Zhiguo Zhou, Weiqing Li, Jiawei Fang, Yejin Zhang, Zhenzhong Chen, Dengwei He
Topics & Concepts
OsteoarthritisMedicineCartilageInflammationExtracellular matrixBone remodelingDegeneration (medical)Signal transductionPharmacologyInternal medicineCancer researchPathologyCell biologyAnatomyBiologyAlternative medicineinterferon and immune responsesCancer-related molecular mechanisms researchCytokine Signaling Pathways and Interactions