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Immune-stimulating antibody conjugates elicit robust myeloid activation and durable antitumor immunity

Shelley E. Ackerman, Cecelia I. Pearson, Joshua D. Gregorio, Joseph C. González, Justin A. Kenkel, Felix J. Hartmann, Angela Luo, Po Y. Ho, Heidi Leblanc, Lisa K. Blum, Samuel C. Kimmey, Andrew Luo, Murray L. Nguyen, Jason C. Paik, Lauren Y. Sheu, Benjamin Ackerman, Arthur Lee, Hai Li, Jennifer Melrose, Richard Laura, Vishnu C. Ramani, Karla A. Henning, David Y. Jackson, Brian S. Safina, Grant Yonehiro, Bruce H. Devens, Yaron Carmi, Steven J. Chapin, Sean C. Bendall, Marcin Kowanetz, David Dornan, Edgar G. Engleman, Michael N. Alonso

2020Nature Cancer203 citationsDOIOpen Access PDF

Topics & Concepts

Immune systemImmunologyAcquired immune systemTumor microenvironmentMyeloidCancer researchTLR7AntibodyImmunotherapyAntigenInnate immune systemBiologyMedicineToll-like receptorImmunotherapy and Immune ResponsesCancer Immunotherapy and BiomarkersImmune Cell Function and Interaction
Immune-stimulating antibody conjugates elicit robust myeloid activation and durable antitumor immunity | Litcius