Horizontal Spread of Rhodococcus equi Macrolide Resistance Plasmid pRErm46 across Environmental <i>Actinobacteria</i>
Sonsiray Álvarez‐Narváez, Steeve Giguère, Londa J. Berghaus, Cody Dailey, José A. Vázquez‐Boland
Abstract
This study demonstrates the efficient horizontal transfer of the Rhodococcus equi conjugative plasmid pRErm46, recently identified as the cause of the emerging macrolide resistance among equine isolates of this pathogen, to and from different environmental Actinobacteria , including a variety of rhodococci as well as Nocardia and Arthrobacter spp. The reported data support the notion that environmental microbiotas may act as reservoirs for the endemic maintenance of antimicrobial resistance in an antibiotic pressurized farm habitat.
Topics & Concepts
RhodococcusActinobacteriaBiologyMicrobiologyPlasmidAntibiotic resistanceNocardiaRhodococcus equiBacteriaArthrobacterHuman pathogenPathogenAntibioticsGenetics16S ribosomal RNAVirulenceDNAGeneInfectious Disease Case Reports and TreatmentsInfections and bacterial resistanceAntibiotic Resistance in Bacteria