Suberanilohydroxamic acid (SAHA), a HDAC inhibitor, suppresses the effect of Treg cells by targeting the c-Myc/CCL1 pathway in glioma stem cells and improves PD-L1 blockade therapy
Ting Sun, Bin Liu, Lize Cai, Youxin Zhou, Wei Yang, Yanyan Li
Topics & Concepts
BlockadeCancer researchTreg cellGliomaMedicineChemistryImmune systemImmunologyT cellInternal medicineReceptorIL-2 receptorHistone Deacetylase Inhibitors ResearchCancer Immunotherapy and BiomarkersGlioma Diagnosis and Treatment