Litcius/Paper detail

A Brief Review on Schiff Base, Synthesis, and Their Antimicrobial Activities

Ruaa M. Dhedan, Sanaa A. Alsahib, Rana Abid Ali

2023Russian Journal of Bioorganic Chemistry18 citationsDOI

Abstract

Abstract The Schiff base chemsitry includes compounds that attracted the attention of research scope from the early years. Consequently, the Schiff base constitutes a significant source of compounds for new pharmacological developments. Several Schiff bases, including derivatives, were synthesized and assessed for biological activities they possess, containing antimicrobial, antioxidant, anti-inflammatory, anti-tuberculosis, anticonvulsants, anxiolytics, antidepressant, anticancer, antihypertensive,and anti-fungal activity. The Schiff Base research, including composites with a lower-side effect, and extra specific activity and remains a dynamic zone of debate in medicinal chemistry. The current wrok elaborately discusses the medicinal chemistry and its bio-logical qualities.

Topics & Concepts

AntimicrobialSchiff baseChemistryCombinatorial chemistryBioorganic chemistryAntioxidantOrganic chemistryStereochemistryEnzymeSynthesis and biological activitySynthesis and Characterization of Heterocyclic CompoundsEnzyme function and inhibition