Litcius/Paper detail

Recent advances of novel fourth generation EGFR inhibitors in overcoming C797S mutation of lung cancer therapy

Li Xu, Bing Xu, Jianshe Wang, Yuan Gao, Xingrui He, Tian Xie, Xiang‐Yang Ye

2022European Journal of Medicinal Chemistry50 citationsDOIOpen Access PDF

Topics & Concepts

OsimertinibLung cancerEpidermal growth factor receptorMedicineCancer researchCancerGefitinibTyrosine kinaseOncologyEGFR inhibitorsDrug resistancePopulationInternal medicineErlotinibBiologyReceptorGeneticsEnvironmental healthProtein Degradation and InhibitorsLung Cancer Treatments and MutationsCancer therapeutics and mechanisms