Neurodegeneration and glial morphological changes are both prevented by TRPM2 inhibition during the progression of a Parkinson's disease mouse model
Ana Flávia Fernandes Ferreira, Henning Ulrich, Zhong‐Ping Feng, Hong‐Shuo Sun, Luiz Roberto Britto
Topics & Concepts
NeuroinflammationNeurodegenerationStriatumSubstantia nigraParkinson's diseaseAmyotrophic lateral sclerosisNeuroscienceMicrogliaDopaminergicMedicineTRPM2AstrogliosisInternal medicinePathologyBiologyDopamineDiseaseCentral nervous systemInflammationTransient receptor potential channelReceptorIon Channels and ReceptorsParkinson's Disease Mechanisms and TreatmentsNeuroinflammation and Neurodegeneration Mechanisms