A strategy of local hydrogen capture and catalytic hydrogenation for enhanced therapy of chronic liver diseases
Geru Tao, Feng Liu, Zhaokui Jin, Boyan Liu, Hao Wang, Daosheng Li, Wei Tang, Yuan Chen, Qianjun He, Shucun Qin
Abstract
Our study verified a catalytic strategy of combining PdH nanoparticles and hydrogen inhalation, which exhibited enhanced anti-inflammatory effect for CLD treatment. The proposed catalytic strategy will open a new window to realize safe and efficient CLD treatment.
Topics & Concepts
SteatohepatitisCirrhosisSteatosisMedicineGlutathioneFibrosisIn vivoPharmacologyChemistryInflammationInternal medicineFatty liverBiochemistryEnzymeBiologyDiseaseBiotechnologyHydrogen's biological and therapeutic effectsBiochemical effects in animalsAnesthesia and Neurotoxicity Research