Design, synthesis and biological evaluation of novel cationic liposomes loaded with melphalan for the treatment of cancer
Mani Sharma, S. S. S. S. Sudha Ambadipudi, Neeraj Kumar Chouhan, Veena Nayak, Srihari Pabbaraja, Sai Balaji Andugulapati, Ramakrishna Sistla
Topics & Concepts
ChemistryCytotoxicityLiposomeDNA fragmentationMelphalanApoptosisDrug deliveryCancer cellPharmacologyCationic polymerizationDrugBiological activityDrug carrierCancerProgrammed cell deathIn vitroBiochemistryMultiple myelomaOrganic chemistryImmunologyBiologyGeneticsRNA Interference and Gene DeliveryNanoparticle-Based Drug DeliveryDendrimers and Hyperbranched Polymers