Development of an Antimicrobial-Coated Absorbable Monofilament Suture from a Medical-Grade Poly(<scp>l</scp>-lactide-<i>co</i>-ε-caprolactone) Copolymer
Montira Sriyai, Jagkrit Tasati, Robert Molloy, Puttinan Meepowpan, Runglawan Somsunan, Patnarin Worajittiphon, Donraporn Daranarong, Jomkwan Meerak, Winita Punyodom
Abstract
, giving a clear inhibition zone range of 20-24 mm for 90 days. Cytotoxicity testing of the drug-coated fibers showed a %viability of more than 70%, indicating that they were nontoxic.
Topics & Concepts
CaprolactoneMaterials scienceUltimate tensile strengthCopolymerFiberLactideNuclear chemistryPolymer chemistryChemistryComposite materialPolymerbiodegradable polymer synthesis and propertiesSurgical Sutures and AdhesivesHemostasis and retained surgical items