Design, synthesis and biological evaluation of novel (E)-2-benzylidene-N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)hydrazine-1-carboxamide derivatives as α-glucosidase inhibitors
Jinhe Zhang, Hong-Xu Xie, Yue Li, Kaiming Wang, Zhiling Song, Kongkai Zhu, Lei Fang, Juan Zhang, Cheng‐Shi Jiang
Topics & Concepts
ChemistryAcarboseCarboxamideCytotoxicityIn vivoIC50StereochemistryHydrazine (antidepressant)Docking (animal)In vitroChemical synthesisBioassayBiological activityEnzymeBiochemistryBiotechnologyMedicineBiologyNursingGeneticsNatural Antidiabetic Agents StudiesCarbohydrate Chemistry and SynthesisBioactive Compounds and Antitumor Agents