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Risk factors for venous thromboembolism and evaluation of the modified Caprini score in patients undergoing lung resection

Songping Cui, Shuo Chen, Hui Li, Lihui Ke, Yi Liu, Ruiheng Jiang, Bin Hu, Tong Li, Yang Wang, Jinbai Miao, Wenqian Zhang

2020Journal of Thoracic Disease17 citationsDOIOpen Access PDF

Abstract

BACKGROUND: There is a high incidence of venous thromboembolism (VTE) after lung resection, so it is necessary to identify the risk factors for VTE in these patients. It is also important to evaluate whether the modified Caprini score can accurately assess the risk of VTE in patients after lung resection. METHODS: This retrospective study included 437 patients undergoing lung resection between July 2016 and December 2017. All patients underwent lower extremities ultrasound before and after operation to determine the presence of the newly diagnosed VTE. RESULTS: /L and 1.37 µg/mL respectively. The modified Caprini score divided the patients into three groups: low risk (0-4 points), moderate risk (5-8 points) and high risk (≥9 points), and the incidence of VTE was 12.3% (37/300), 7.5% (10/133) and 0% (0/4), respectively (P>0.05). CONCLUSIONS: In this study, we identified four independent factors for VTE after lung resection patients: age, duration of operation, lymphocyte count, and D-dimer. According to the modified Caprini score, there were fewer patients in the high-risk group, and the incidence of VTE not increased with the increase of risk. Better evaluation of operation time and D-dimer may help the modified Caprini score to better assess VTE risk in these patients.

Topics & Concepts

MedicineReceiver operating characteristicIncidence (geometry)Logistic regressionInternal medicineLungRetrospective cohort studyVenous thromboembolismLung cancerGastroenterologySurgeryThrombosisOpticsPhysicsVenous Thromboembolism Diagnosis and ManagementCardiac tumors and thrombiInflammatory Biomarkers in Disease Prognosis