Hydrogen peroxide-responsive AIE probe for imaging-guided organelle targeting and photodynamic cancer cell ablation
Qian Wu, Youmei Li, Youmei Li, Ying Li, Ying Li, Dong Wang, Ben Zhong Tang
Abstract
A versatile red/near-infrared AIE probe, <bold>TTPy-H2O2</bold> , was developed for the specific visualization of H <sub>2</sub> O <sub>2</sub> with mitochondria targeting ability, meanwhile achieving efficient photodynamic therapy for cancer cells.
Topics & Concepts
Photodynamic therapyHydrogen peroxideOrganelleCancer cellAblationMaterials scienceCancerNanotechnologyCancer researchChemistryBiophysicsPhotochemistryMedicineBiochemistryBiologyInternal medicineOrganic chemistryNanoplatforms for cancer theranosticsLuminescence and Fluorescent MaterialsMolecular Sensors and Ion Detection