Monitoring innate immune cell dynamics in the glioma microenvironment by magnetic resonance imaging and multiphoton microscopy (MR-MPM)
Kianush Karimian‐Jazi, Philipp Münch, A. Alexander, Manuel Fischer, Kira Pfleiderer, Manuel Piechutta, Matthia A. Karreman, Gergely Solecki, Anna S. Berghoff, Mirco Friedrich, Katrin Deumelandt, Felix T. Kurz, Wolfgang Wick, Sabine Heiland, Martin Bendszus, Frank Winkler, Michael Platten, Michael O. Breckwoldt
Abstract
Our approach allows innate immune cell tracking by MRI and multiphoton microscopy in the same animal to longitudinally investigate innate immune cell dynamics in the TME.
Topics & Concepts
Magnetic resonance imagingInnate immune systemMultiphoton fluorescence microscopeNuclear magnetic resonanceTumor microenvironmentImmune systemChemistryMedicinePhysicsFluorescence microscopeImmunologyOpticsRadiologyFluorescenceImmune cells in cancerNeuroinflammation and Neurodegeneration MechanismsExtracellular vesicles in disease