Medicinal attributes of pyridine scaffold as anticancer targeting agents
Esraa A. Mohamed, Nasser S. M. Ismail, Mohamed Hagras, Hanan M. Refaat
Abstract
Abstract Background The heterocyclic compounds particularly pyridine displayed clinical and biological implementation. Pyridine scaffolds have been detected in most relevant drug molecules that included pyridine provided a great possibility for treatment. Main text Pyridine-containing compounds have increasing importance for medicinal application as antiviral, anticholinesterase activities, antimalarial, antimicrobial, antidiabetic and anticancer. This has generated concern among researchers in synthesising a variety of pyridine derivatives. Conclusion This review focuses on different pyridine targets as anticancer and their pharmacophoric elements controlling its activity.