Saikosaponin-D Mitigates Oxidation in SH-SY5Y Cells Stimulated by Glutamate Through Activation of Nrf2 Pathway: Involvement of PI3K
Jikun Du, Daibo Song, Yuanhua Li, Jierong Liu, Xiaoman Huang, Baohong Li, Li Li
Topics & Concepts
Oxidative stressNeurotoxicitySH-SY5YChemistryReactive oxygen speciesNeuroprotectionTroloxPhosphatidylinositolViability assayBiochemistryPI3K/AKT/mTOR pathwayPharmacologyMalondialdehydeGlutamate receptorMTT assayMolecular biologyApoptosisSignal transductionBiologyCell cultureToxicityReceptorAntioxidant capacityNeuroblastomaOrganic chemistryGeneticsGenomics, phytochemicals, and oxidative stressNatural product bioactivities and synthesisAlzheimer's disease research and treatments