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Co-development of mesoderm and endoderm enables organotypic vascularization in lung and gut organoids

Yifei Miao, Nicole Min Qian Pek, Cheng Tan, Cheng Jiang, Zhiyun Yu, Kentaro Iwasawa, Min Shi, Daniel O. Kechele, Nambirajan Sundaram, Victor Pastrana-Gomez, Débora Sinner, Xingchen Liu, Kevin Lin, Cheng-Lun Na, Keishi Kishimoto, Min-Chi Yang, Sushila Maharjan, Jason Tchieu, Jeffrey A. Whitsett, Yu Shrike Zhang, Kyle W. McCracken, Robbert J. Rottier, Darrell N. Kotton, Michael A. Helmrath, J. Michael Wells, Takanori Takebe, Aaron M. Zorn, Ya‐Wen Chen, Minzhe Guo, Mingxia Gu

2025Cell54 citationsDOIOpen Access PDF

Topics & Concepts

BiologyEndodermOrganoidMesodermMesenchymeCell biologyStem cellProgenitor cellInduced pluripotent stem cellKLF4TransplantationCellular differentiationEmbryonic stem cellMesenchymal stem cellInternal medicineGeneticsMedicineGeneRenal and related cancersNeonatal Respiratory Health ResearchCongenital heart defects research
Co-development of mesoderm and endoderm enables organotypic vascularization in lung and gut organoids | Litcius